Although it is not searchable online, many of the families that are mentioned in it have been documented on this site and on others since Retoños' publication in 2010-2011:

• Nuestros Ranchos
• FamilySearch
• Guadalajara Dispensas
• Katy's Guadalajara Dispensas
• Katy's Other Indexes
• Valladolid Dispensas
• Wikitree

This list of the surnames mentioned in Retoños was shared here before by other researchers. Review it and consider adding to your post which surname or chapter you are most interested in and perhaps I or someone else here can point you to what you're looking for. The more information you provide about your "brick wall" ancestors, the easier it is for others to help you.

1.- Aceves
2.- Alba (de)
3.- Alcalá y Mendoza
4.- Aldrete
5.- Alvarez del Castillo
6.- Alvarez-Tostado
7.- Anava
8.- Anda-Altamirano (de)
9.- Aranda
10.- Ascencio de León
11.- Azuela de San Palayo (de la)
12.- Camacho-Riquelme
13.- Camarena
14.- Carlín
15.- Casillas y Cabrera
16.- Cuéllar
17.- Chávez-Fragoso
18.- Díaz del Castillo
19.- Díaz